Evaluation of Environmental Microbial Contamination and Effectiveness of Cleaning Protocols in Controlled Manufacturing Environments
- 1Department of Microbiology, Indfrag Biosciences Private Limited, Tamil Nadu, India
- 2Department of Microbiology, MGR College, Dr. MGR Nagar, Tamil Nadu, India
- 3Department of Biotechnology, School of Life Sciences, Vels Institute of Science, Technology and Advanced Studies (VISTAS), Pallavaram, Chennai, India
* Correspondence: palanivelan2012@gmail.com; prakazbt@gmail.com
Abstract
Environmental microbial monitoring program is an essential protocol to ensuring the safety, and quality of food-grade and cosmetic-grade products derived from plant-based extracts. This study uses air and surface sampling techniques to evaluate the microbial contamination risks in the product contact surface areas. The data collected through settle plates, manual swabs, and ATP tester/Luminometer, highlights the microbial risk assessment and implementation of hygiene protocols in critical areas. This study highlights best practices and improvement measures for contamination control by classifying clean room zones and utilizing quantitative microbial risk assessment models.
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© 2026 The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, provided the original author(s) and the source are credited.