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IJAIDR International Journal of Advances in Interdisciplinary Research eISSN 2348-0696 · Bi-monthly · Open Access · Since 2013
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All articles published in IJAIDR, newest first. Articles are published online as soon as they are ready.

All Research Article (14) Review Article (10) Short Communication (1)
Review Article Open Access 15 May 2025

Computational Approaches for Predicting the Biological Activities of Phytochemicals: Advances and Challenges

Naveena Sakthivel and Gnanendra Shanmugam
Int J Adv Interdis Res 2025, 5: e005 · DOI: registration in progress

Phytochemicals, a diverse class of bioactive compounds derived from plants, play a pivotal role in modern drug discovery and natural product research. The ability to accurately predict their biological activities based on chemical structure is essential for enhancing screening efficiency and minimizing experimental costs. This review presents an overview of…

Review Article Open Access 12 May 2025

Transforming Lung Cancer Management with AI and Biomarkers: From Early Detection to Targeted Therapies

Priyadharshini Balasubramani and Gnanendra Shanmugam
Int J Adv Interdis Res 2025, 5: e004 · DOI: registration in progress

Lung cancer remains the leading cause of cancer-related mortality worldwide, with non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) representing the primary histological subtypes. Approximately 85% of cases are classified as NSCLC, whereas SCLC is characterized by its aggressive clinical course and poor prognosis. Major risk factors for S…

Review Article Open Access 11 May 2025

From Dysbiosis to Therapy: The Role of Gut Microbiota-Derived Metabolites in IBD

Janet Jessica A and Gnanendra Shanmugam
Int J Adv Interdis Res 2025, 5: e012 · DOI: registration in progress

Inflammatory Bowel Disease (IBD), encompassing Crohn’s disease and ulcerative colitis, is a chronic disorder of the gastrointestinal tract characterized by recurrent inflammation and dysregulated immune responses. Emerging evidence highlights the crucial role of gut microbiota and their metabolites in both the pathogenesis and potential treatment of IBD. Th…

Research Article Open Access 22 February 2025

Identification of Multi-epitopes as an effective vaccine against Chikungunya virus: An Immunoinformatics Study

Nivetha B, Tamil Bharathi V and Gnanendra TS
Int J Adv Interdis Res 2025, 5: e003 · DOI: registration in progress

Chikungunya, a virus that is transmitted to humans by the bite of an infected mosquito. Chikungunya is caused by the Chikungunya virus (CHIKV), an RNA virus belonging to the alphavirus genus and Togaviridae family. The term Chikungunya comes from the Kimakonda language and means "to become contorted." The most common symptoms include fever, headache, and jo…

Research Article Open Access 20 February 2025

A Comprehensive analysis of phytochemicals in Asparagus racemosus extracts and their Antioxidant, Anticancer activities, and Apoptosis induction

Perumal R and Subana S
Int J Adv Interdis Res 2025, 5: e002 · DOI: registration in progress

Cancer remains one of the leading causes of morbidity and mortality worldwide, driven by uncontrolled cell proliferation and resistance to apoptosis. Despite significant advances in cancer treatment, including surgery, chemotherapy, and radiation therapy, challenges such as drug resistance and adverse side effects continue to limit their effectiveness. Cons…

Research Article Open Access 20 February 2025

Green synthesis and characterization of copper nanoparticles using Bauhinia variegata extracts: Antibacterial efficacy against Diabetic wound pathogens

Priya G and Subana S
Int J Adv Interdis Res 2025, 5: e001 · DOI: registration in progress

The green synthesis of copper nanoparticles (CuNPs) using Bauhinia variegata leaf extract presents a cost-effective and environmentally sustainable approach to developing alternative antimicrobial agents. Bauhinia variegata is a medicinal plant rich in bioactive compounds, including anthraquinones, flavonoids, phenolic glycosides, alkaloids, saponins, reduc…

Research Article Open Access 24 September 2024

Comparative Analysis of Aquaponic, Hydroponic, and Geoponic Systems for Greenhouse Cultivation of Vigna radiata and Centella asiatica

Sujitha Arunraj and Berciyal Golda Peter
Int J Adv Interdis Res 2024, 4: e140 · DOI: registration in progress

Aquaponics is a technology within the integrated agri-aquaculture systems discipline that combines animal and plant culture to optimize resource conservation, nutrient cycling, and overall efficiency. This study compares plant growth across three cultivation methods of hydroponics, aquaponics, and soil-based (geoponics)over a 45-day period, focusing on Vign…

Research Article Open Access 20 September 2024

Exploring the Potential of Cocos nucifera Phytochemicals in the Effective Management of Breast Cancer via ER-Alpha Targeting

Deenatharani Shanmugam, Amsaveni Kuppusamy and Berciyal Golda Peter
Int J Adv Interdis Res 2024, 4: e138 · DOI: registration in progress

Cocos nucifera L., commonly referred to as the coconut tree, is a vital plant in tropical and subtropical regions and is often called the "tree of life" due to its many uses and health benefits. Historically, coconut products have played a key role in traditional Indian medicine for treating conditions like bronchitis, gingivitis, and tumors. Known for its …

Short Communication Open Access 25 March 2024

Comparative Genomics of SARS-CoV and SARS-CoV-2 Using Fuzzy Sets: Insights into Viral Therapeutic Implications

Tamil Bharathi Viswanathan, Anitha Devi Dinakaran and Gnanendra Shanmugam
Int J Adv Interdis Res 2024, 4: e132 · DOI: registration in progress

Severe acute respiratory syndrome coronavirus (SARS-CoV) and the 2019 novel coronavirus (SARS-CoV-2) are highly infectious pathogens that primarily affect the human respiratory system, causing a range of respiratory illnesses from mild to severe. The SARS-CoV outbreak in 2003 resulted in significant global fatalities, while the ongoing COVID-19 pandemic, ca…

Review Article Open Access 24 March 2024

A Comprehensive review of Medicinal Plant Database, Drug Discovery, and Model Organism Databases: Insights into Biomedical Research

Menaka Karuppannan, Swathi Sakthivel and Gnanendra Shanmugam
Int J Adv Interdis Res 2024, 4: e125 · DOI: registration in progress

In this review, our focus is on biomedical research database that are reported housed mostly by the National institute of Health of the United States .This review presents an overview of three critical domains in biomedical research: medicinal plant databases, drug discovery databases, and model organism databases. By compiling these sources, we aimed to pu…