Review Article
Open Access 11 September 2026
Subiksha Periyasamy and Berciyal Golda Peter
Int J Adv Interdis Res 2026, 6: e004 · DOI: registration in progress
Microbial cell factories—microorganisms reprogrammed to convert renewable feedstocks into value-added molecules—have become central to modern bioprocessing engineering. Advances in systems and synthetic biology, genome editing and high-throughput screening now permit the rational design of strains that manufacture fuels, bulk and fine chemicals, pharmaceuti…
Review Article
Open Access 20 December 2025
Vijay Kadam, Abhijit Barate, Tejas Shende, Vidya Nimbalkar, Gokul Sonawane, Mahesh Rangnekar, Sanjay Bhalerao and Shalaka Salvekar
Int J Adv Interdis Res 2025, 5: e017 · DOI: registration in progress
Anestrus, defined as the absence of overt estrus or heat signs, is a major reproductive disorder affecting cattle and buffaloes in India, significantly impacting fertility and productivity in the livestock sector. In India, where buffaloes constitute a large portion of the dairy industry, anestrus is particularly prevalent due to their inherent reproductive…
Review Article
Open Access 20 December 2025
Vijay Kadam, Abhijit Barate, Tejas Shende, Vidya Nimbalkar, Gokul Sonawane, Mahesh Rangnekar, Sanjay Bhalerao and Shalaka Salvekar
Int J Adv Interdis Res 2025, 5: e016 · DOI: registration in progress
Reproductive efficiency is a critical determinant of productivity in small ruminants, particularly sheep and goats, which are integral to the livelihood of rural farmers in India. However, various reproductive disorders significantly impact fertility, kidding/lambing rates, and overall herd profitability. This review highlights the prevalence, etiology, cli…
Review Article
Open Access 20 May 2025
Swedha Ambigapathi and Gnanendra Shanmugam
Int J Adv Interdis Res 2025, 5: e010 · DOI: registration in progress
The rhizosphere represents a highly dynamic interface where plant roots interact with the surrounding soil matrix, fostering a diverse and functionally complex microbial community. These microbiota play essential roles in plant growth promotion, nutrient cycling, and resilience to biotic and abiotic stresses. In recent years, plant-associated microbial comm…
Review Article
Open Access 19 May 2025
Sowmiya Anandan and Gnanendra Shanmugam
Int J Adv Interdis Res 2025, 5: e009 · DOI: registration in progress
CRISPR-Cas9 technology has rapidly emerged as a transformative tool in breast cancer research, enabling precise genome editing that advances functional genomics, target discovery, and therapeutic development. This review highlights the fundamental principles of CRISPR-Cas9 and its diverse applications in breast cancer models, including gene function interro…
Review Article
Open Access 17 May 2025
Tamil Bharathi Viswanathan and Gnanendra Shanmugam
Int J Adv Interdis Res 2025, 5: e006 · DOI: registration in progress
Microbial metabolites are bioactive compounds produced by microorganisms, which plays a crucial role in biotechnology, pharmaceuticals, and natural product research. The rapid advancements in high-throughput sequencing, mass spectrometry, and NMR spectroscopy have led to an exponential increase in metabolite data making efficient data management essential. …
Review Article
Open Access 15 May 2025
Naveena Sakthivel and Gnanendra Shanmugam
Int J Adv Interdis Res 2025, 5: e005 · DOI: registration in progress
Phytochemicals, a diverse class of bioactive compounds derived from plants, play a pivotal role in modern drug discovery and natural product research. The ability to accurately predict their biological activities based on chemical structure is essential for enhancing screening efficiency and minimizing experimental costs. This review presents an overview of…
Review Article
Open Access 12 May 2025
Priyadharshini Balasubramani and Gnanendra Shanmugam
Int J Adv Interdis Res 2025, 5: e004 · DOI: registration in progress
Lung cancer remains the leading cause of cancer-related mortality worldwide, with non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) representing the primary histological subtypes. Approximately 85% of cases are classified as NSCLC, whereas SCLC is characterized by its aggressive clinical course and poor prognosis. Major risk factors for S…
Review Article
Open Access 11 May 2025
Janet Jessica A and Gnanendra Shanmugam
Int J Adv Interdis Res 2025, 5: e012 · DOI: registration in progress
Inflammatory Bowel Disease (IBD), encompassing Crohn’s disease and ulcerative colitis, is a chronic disorder of the gastrointestinal tract characterized by recurrent inflammation and dysregulated immune responses. Emerging evidence highlights the crucial role of gut microbiota and their metabolites in both the pathogenesis and potential treatment of IBD. Th…
Review Article
Open Access 24 March 2024
Menaka Karuppannan, Swathi Sakthivel and Gnanendra Shanmugam
Int J Adv Interdis Res 2024, 4: e125 · DOI: registration in progress
In this review, our focus is on biomedical research database that are reported housed mostly by the National institute of Health of the United States .This review presents an overview of three critical domains in biomedical research: medicinal plant databases, drug discovery databases, and model organism databases. By compiling these sources, we aimed to pu…